Distal Femoral Giant cell tumour of bone: intra-lesional curettage and stabilisation surgical technique
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Giant cell tumour of bone is a rare, benign primary bone tumour arising in the meta-epiphyseal region of bones in young adults.This tumour classically arises in the meta-epiphyseal region as a radiolucent lesion most commonly affecting the distal femur, proximal tibia, proximal humerus and distal radius.
Surgical treatment involves intralesional curettage with or without internal fixation or en-bloc resection and limb-salvage reconstruction. The decision on the type of surgical treatment to undertake in a patient with GCTB depends on a variety of factors including the Campanacci staging at diagnosis, articular involvement and anatomical location.
Denosumab has recently played a role in the management of GCTB but the optimal use of denosomab has yet to be identified. Denosumab is a monoclonal antibody to RANK ligand recommended as the first option in inoperable or metastatic GCTB. Denosumab has also been used pre-operatively to downstage tumours with large soft tissue extension to allow for less morbid surgery.
Author: Mr Jonathan Stevenson FRCS (Tr & Orth)
Institution: The Royal Orthopaedic Hospital ,Birmingham ,UK.
- Each operation and the questions associated become named course in the CPD section
- The operative technique itself is read as a lesson as is any company implant information if this is being assessed.
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The pass mark is 75%.
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Welcome to the Professional Development question section. The objective of taking these tests is to demonstrate that you have understood all aspects of the assessment and management of patients requiring surgical intevention. On successful completion you will receive a certificate accredited by both the Royal College of Surgeons of both England and Edinburgh as well as the British Orthopaedic Association.
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